From Harvard Health Newsletter
FDA study gets to the heart of medicine expiration and safety
Updated: September 2, 2015
This is a dilemma many people face in some way or another. A column published in Psychopharmacology Today offers some advice.
It turns out that the expiration date on a drug does stand for something, but probably not what you think it does. Since a law was passed in 1979, drug manufacturers are required to stamp an expiration date on their products. This is the date at which the manufacturer can still guarantee the full potency and safety of the drug.
Most of what is known about drug expiration dates comes from a study conducted by the Food and Drug Administration at the request of the military. With a large and expensive stockpile of drugs, the military faced tossing out and replacing its drugs every few years. What they found from the study is 90% of more than 100 drugs, both prescription and over-the-counter, were perfectly good to use even 15 years after the expiration date.
So the expiration date doesn’t really indicate a point at which the medication is no longer effective or has become unsafe to use. Medical authorities state if expired medicine is safe to take, even those that expired years ago. A rare exception to this may be tetracycline, but the report on this is controversial among researchers. It’s true the effectiveness of a drug may decrease over time, but much of the original potency still remains even a decade after the expiration date. Excluding nitroglycerin, insulin, and liquid antibiotics, most medications are as long-lasting as the ones tested by the military. Placing a medication in a cool place, such as a refrigerator, will help a drug remain potent for many years.
Is the expiration date a marketing ploy by drug manufacturers, to keep you restocking your medicine cabinet and their pockets regularly? You can look at it that way. Or you can also look at it this way: The expiration dates are very conservative to ensure you get everything you paid for. And, really, if a drug manufacturer had to do expiration-date testing for longer periods it would slow their ability to bring you new and improved formulations. (“New and improved” often means same drug with a slight alteration, but a new name, new advertising campaign and much higher price!)
The next time you face the drug expiration date dilemma, consider what you’ve learned here. If the expiration date passed a few years ago and it’s important that your drug is absolutely 100% effective, you might want to consider buying a new bottle. And if you have any questions about the safety or effectiveness of any drug, ask your pharmacist. He or she is a great resource when it comes to getting more information about your medications.
From CNN MONEY / A special drug
Globally, more than 130 million people are estimated to be living with Hepatitis C. Left untreated, the disease can be deadly. But sofosbuvir, released in late 2013 by U.S. biopharmaceutical firm Gilead ((Along with a barrage of nonstop ads on TV for “Harvoni” – hyped as a cure now available to everyone)), is effectively a cure.
It’s also expensive, costing $84,000 for a 12-week course in the U.S. Doctors often prescribe the drug — sold under the brand names Sovaldi and Harvoni — in combination with others, further raising the overall cost of treatment.
As a result, insurers and government healthcare providers often pay for its use in only their sickest patients.
But in India, a 12-week course of the drug’s generic version can be purchased for just $500.